Antibiotics in Animals Tied to Risk of Human Infection

A federal analysis of 30 antibiotics used in animal feed found that the  majority of them were likely to be contributing to the growing problem of bacterial infections that are resistant to treatment in people, according to documents released Monday by a health advocacy group.

... scientists from the F.D.A. studied 30 penicillin and tetracycline additives in animal feed. They found that 18 of them posed a high risk of exposing humans to antibiotic-resistant bacteria through food.

Resistant bacteria make it difficult and sometimes impossible to treat infections with ordinary antibiotics. The scientists did not have enough data to judge the other 12 drugs.

At least two million Americans fall sick every year and about 23,000 die from antibiotic-resistant infections, the Centers for Disease Control and Prevention estimates. Representatives of the food industry largely blame hospitals and treatments given to people for the rise of deadly superbugs. But many scientists believe that indiscriminate use of antibiotics in animal feed is a major contributor.

Farmers and ranchers feed small amounts of the drugs to animals over their lifetimes to keep them healthy in crowded conditions, causing bacteria to develop a resistance passed on to people through the environment and eating meat from the animals.

The F.D.A. has tried repeatedly to rein in the use of the drugs in animals. It adopted regulations in 1973 that required companies to submit studies showing that a drug’s use in animal feed did not promote resistance in people.

In 1977, the agency proposed withdrawing approvals for animal feed additives containing penicillin and most tetracyclines, but it never followed through, said Avinash Kar, a lawyer for the Natural Resources Defense Council. The group sued the agency in 2012 to try to force it to carry out the 1977 proposal.

“This is an agency that has repeatedly found, since the 1970s, that these drugs pose a risk to human health, but it has not done anything meaningful with those conclusions,” Mr. Kar said.

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